![]() NS4A is a cofactor of NS3 protease activity. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. ![]() ![]() Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. Version 2.73 32286-7 Hepatitis C virus genotype in Serum or Plasma by NAA with probe detection Active Part Description ![]()
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